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KMID : 1138520080110020055
Journal of Pharmacopuncture
2008 Volume.11 No. 2 p.55 ~ p.62
Clinical Studies of Sweet Bee Venom to the Effect of Abdominal Fat Accumulation
Lim Chung-San

Park Won-Pil
Jang Seong-Bong
Choi Young-Chon
Park Do-Il
Kwon Ki-Rok
Lee Hee-Choon
Abstract
Objective : Sweet bee venom is made by removing allergen from the bee venom through gel filtration chromatography and propionic acid/urea polyacrylamide gel electrophoresis. The aim of this study was to verify allergy inhibitory action in Sweet Bee Venom(SBV) and New Sweet Bee Venom(NSBV) removed enzymes and compounds of low molecular weight.

Methods : 84 healthy adult men and women were selected through a survey whom had never received the bee venom therapy in the past. The concentration of Normal Saline, SBV and NSBV pharmacopuncture was equally at 0.1mg/mL and the experiment was conducted as the double blind test.

Results : Participants of the study was comprised of 63 men and 21 women with the average age of 28.3 years. According to results of pain sense, SBV group showed significant higher score compared with NS group and NSBV group using VAS in treating time. And SBV and NSBV group showed significant higher score compared with NS group after 30 minutes. Other allergic responses were insignificant between the groups.

Conclusions : As a result of removed allergen and compounds of low molecular weight, NSBV significantly inhibits pain sense in treating time compared with SBV. This indicates wider and easier application of NSBV for the useful application in clinical treatment. Further comparative studies should be conducted to yield more objective verification.
KEYWORD
Bee Venom, Sweet Bee Venom, New Sweet Bee Venom, double blind test, allergy response, pain sense
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